Practice question

MCQ

Question

Given below are two statements regarding Major Histocompatibility Complex (MHC). Statement I: MHC I contains two different polypeptide chains – α chain and β chain. Statement II: MHC I is present on all nucleated cells. In the light of the above two statements, select the most appropriate answer from the options given below:

Options

Choose one · Correct answer highlighted

Both Statement I and Statement II are correct Statement I is correct but Statement II is incorrect Statement I is not correct but Statement II is correct Correct Both Statement I and Statement II are not correct

Explanation

MHC class I consists of heavy α chain with three domains plus noncovalently associated β2-microglobulin, not α plus β chain as in MHC II. It is expressed on all nucleated cells presenting endogenous antigens, so statement I false, II true.

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