Practice question
Question
Consider that you have collected X-ray diffraction data on three different protein crystals, referred to as Protein A, B and C. Data set for crystal A has the best diffraction spot at 8A, crystal B at 5A and crystal C has the best diffraction at 3A. Which data set is likely to yield a higher resolution crystal structure?
Explanation
The principle of enzyme catalysis and lipid structure explains that substrate affinity, transition state stabilization and phospholipid composition govern function. Hence Crystal C fits best because it reflects catalytic efficiency and membrane organization, as documented in authoritative sources on biochemistry.
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