Practice question
Question
Which one of the following sets of protein factors, named as Yamanaka factors, can be used to convert mammalian somatic cells into induced pluripotent stem cells?
Explanation
The principle of enzyme catalysis and lipid structure explains that substrate affinity, transition state stabilization and phospholipid composition govern function. Hence Oct3/4, Sox2, Klf4, c-Myc fits best because it reflects catalytic efficiency and membrane organization, as documented in authoritative sources on biochemistry.
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