Practice question

MCQ

Question

Inhibition of succinic dehydrogenase by malonic acid is

Options

Choose one · Correct answer highlighted

Non-competitive inhibition Competitive inhibition Correct Un-competitive inhibition Feedback inhibition

Explanation

Malonate structurally resembles succinate and competes for active site of succinate dehydrogenase in TCA cycle. It increases apparent Km without affecting Vmax, reversible by excess substrate, classic example of competitive inhibition in mitochondrial complex II.

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