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Question

In a gastrocnemius-sciatic (nerve-muscle) preparation electrical stimulation of the nerve caused twitching of the muscle. Direct stimulation of the muscle also caused twitching. When curare (a cholinergic antagonist) was applied in the bath where the preparation was maintained and the nerve was stimulated, the muscle twitch was not seen. However, under these conditions, if the muscle was stimulated directly, it twitched. These observations suggest that

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Explanation

The principle of quantitative reasoning explains that ratio, percentage and series logic determine correct calculation. Hence stimulation of the nerve was communicated to the muscle through the mediation... fits best because it meets mathematical and logical criteria, as documented in authoritative sources on aptitude and reasoning.

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