Practice question
Question
Glycolysis is the breakdown of glucose to pyruvate, and gluconeogenesis is the synthesis of glucose from pyruvate. The intermediates involved in these two pathways are the same, but only some of the reactions are reversible, and those are catalyzed by the same enzymes. Which of the following steps is catalyzed by two different enzymes for the two pathways?
Explanation
The principle of enzyme catalysis and lipid structure explains that substrate affinity, transition state stabilization and phospholipid composition govern function. Hence Interconversion of glucose and glucose-6-P. fits best because it reflects catalytic efficiency and membrane organization, as documented in authoritative sources on biochemistry.
Discussion
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