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Question

Emmanuelle Charpentier and Jennifer A. Doudna have been awarded the Nobel Prize in Chemistry in 2020 for their work on:

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Explanation

Charpentier and Doudna elucidated bacterial adaptive immune mechanism and repurposed it into programmable genome editing tool. Their CRISPR-Cas9 system uses guide RNA to direct Cas9 nuclease creating double-strand breaks at targeted loci, revolutionizing molecular biology and therapeutics, recognized by 2020 Chemistry Nobel.

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