Practice question
Question
DNA and RNA polymerase differ in ALL of the following, EXCEPT:
Explanation
Both DNA and RNA polymerases catalyze identical nucleophilic attack of 3'-OH on alpha-phosphate of incoming NTP, forming phosphodiester bonds. They diverge in substrates (dNTPs vs NTPs), proofreading and error rates, processivity, and requirement for primer versus de novo initiation.
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