Practice question
Question
A monoclonal antibody binds to G-actin but NOT to Factin. What does this tell you about the epitope recognized by the antibody?
Explanation
The principle of antibody structure explains that immunoglobulin fold with antiparallel beta-sandwich provides antigen binding. Hence The epitope is likely to be a structure that is buried when Gactin polymerize... fits best because it demonstrates immune recognition architecture, as documented in authoritative sources on immunology.
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