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#adenine

6 public questions tagged with this topic.

Deamination of adenine produces

Deamination of adenine at C6 position converts adenine to hypoxanthine, purine retaining six-membered ring but bearing O6 carbonyl instead of amino group, resembling guanine pairing behavior. Hypoxanthine forms stable base pair with cytosine through two hydrogen bonds rather than thymine, prompting incorporation of C opposite lesion during replication. Subsequent synthesis places G opposite C, converting original A:T to G:C transition. Nitrous acid and alkaline conditions promote such deamination, and hypoxanthine removal relies on alkyladenine glycosylase in base excision repair. This principle illustrates essential molecular mechanisms governing replication fidelity and mutation fixation relevant for exam interpretation.

Ref: Lehninger Principles of Biochemistry, 8th ed., Chapter 8: Adenine Deamination to Hypoxanthine

DNA

The purine bases in DNA are:

Adenine and Guanine is the scientifically accurate answer to this question. Within the study of Nucleic Acid, this concept is well-established through extensive research and is documented in standard scientific literature. The specific properties, mechanisms, or characteristics of Adenine and Guanine directly address what is being asked. Among the other options, Adenine and Thymine, Cytosine and Guanine, and Uracil and Thymine do not correctly answer this question because they either refer to different concepts, describe properties of other molecules or processes, or represent common misconceptions about this topic.

Ref: Campbell Biology, Urry et al., 12th Ed.