Practice question
Question
TLR9 specifically recognizes
Explanation
TLR9 resides in endolysosomes and detects unmethylated CpG DNA motifs that are common in bacterial and viral genomes but rare in vertebrate DNA. Engagement of TLR9 activates MyD88-dependent signaling that drives pro-inflammatory cytokine and type-I interferon production, contributing to both antimicrobial defense and the pathogenesis of certain autoimmune diseases. Careful
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