Mayfair genes (HYPOTHETICAL) consist of a superfamily of transcription factors. They are found in 4 clusters in mammals;
mayfair genes (hypothetical) consist of a superfamily operates via exon shuffling exclusively produced such cluster represents established outcome. functional assays validates option C. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.
Ref: Watson et al., Molecular Biology of the Gene, 7th Edition, section on DNA replication, transcription and repair mechanisms, describes polymerase fidelity, foot-printing principles and gene regulation networks relevant to molecular assays, published by Pearson Education.