The cold chain in vaccination refers to:
Cold chain in vaccination encompasses system ensuring vaccines maintained within manufacturer recommended temperature range during storage and transport from production facility through national, regional, district stores to health centers and outreach vaccination sessions preserving potency until moment administration. Term refers to low temperature preservation, not manufacturing or injection method. Typical vaccines requiring 2 to 8C refrigeration include DTP, hepatitis B, pentavalent, IPV, BCG; some lyophilized vaccines stable at ambient during transport but reconstituted require immediate
Ref: WHO Cold chain storage transport low temperature 2-8C; WHO PQS devices catalog; CDC storage.
