Skip to content
Login Register

#tuberculosis

8 public questions tagged with this topic.

Vaccine

BCG vaccine is administered via:

BCG vaccine is administered via intradermal route which is uniquely specified among routine childhood immunizations. Technique involves injection of small volume 0.05 ml for infants under 12 months and 0.1 ml for older children into superficial dermis of lower insertion of deltoid muscle left arm using 26G or 27G needle inserted bevel upward at approximately 10-15 degree angle pushing needle 2 mm subepidermal creating characteristic peau d orange wheal 6-8 mm bleb that disappears within 30 minutes indicating correct placement. Dermis abundant in Langerhans cells expressing langerin CD207 and d

Ref: WHO BCG vaccine position paper 2018 intradermal; Plotkin BCG route; CDC intradermal.

View Details
Microbial Classification

Which phylum includes Mycobacterium tuberculosis?

Mycobacterium tuberculosis belongs to phylum Actinobacteria, also called Actinomycetota, defined as high G+C Gram-positive bacteria typically ranging 60 to 75 mol percent guanine-cytosine content. Members exhibit complex filamentous growth, mycolic acid-containing cell envelope conferring acid-fastness, slow growth rates, and resistance to desiccation and disinfectants. Actinobacterial 16S rRNA signatures and genome GC content cluster Mycobacterium with Streptomyces, Corynebacterium, and Nocardia. This lineage possesses unique arabinogalactan peptidoglycan and lipoarabinomannan, distinguishing

Ref: Campbell Biology 12th ed., Chapter 27 Actinobacteria high GC Mycobacterium; Tortora Microbiology Chapter 11 Actinomycetes acid-fastness

View Details