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#Roundup Ready crops

2 public questions tagged with this topic.

Transgenic Plant -1

EPSPS gene used in Roundup Ready crops was obtained from:

Glyphosate tolerance technology relies on EPSPS variant showing high glyphosate insensitivity while retaining catalytic activity. Soil bacteria from glyphosate production plant waste in Louisiana screened for EPSPS activity in presence of herbicide identified Agrobacterium sp. strain CP4, now classified as Agrobacterium tumefaciens, harboring class II EPSPS naturally tolerant due to structural changes in active site reducing binding affinity. Gene cloned, sequenced, and fused to chloroplast transit peptide from petunia EPSPS and enhanced 35S promoter, introduced into crops via Agrobacterium me

Ref: Barry US Patent 5633435 CP4 EPSPS; Funke PNAS 2006 structure; NCBI NBK131103 Agrobacterium CP4; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482475/

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Transgenic Plant -1

Roundup Ready crops are resistant to:

Roundup Ready is brand name for transgenic crops tolerant to glyphosate based herbicide Roundup. Native crop EPSPS inhibited by glyphosate application, blocking aromatic amino acid synthesis. Incorporation of insensitive EPSPS variant allows continued pathway function despite spray, enabling post-emergence weed control without crop injury. Crops carrying cp4-epsps gene survive broadcast over-the-top application at commercial rates, simplifying weed management and facilitating conservation tillage reducing soil erosion. Soybean, cotton, maize, canola, alfalfa, and sugar beet versions deregulate

Ref: Dill GM Crops 2005 Roundup Ready; Funke PNAS 2006 CP4; NCBI NBK131103; ISAAA Pocket K 10 herbicide tolerance mechanism.

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