Redifferentiation refers to:
Redifferentiation signifies regaining of specialized structure and function by previously dedifferentiated callus cells. Initially mature parenchyma under high auxin reverts to meristematic state through dedifferentiation, reactivating cyclins, CDKs, and chromatin remodeling factors that restore mitotic competence. Redifferentiation reverses this process: random proliferation slows, polarity is re-established via PIN-mediated polar auxin transport creating gradients that pattern tissues. Transcriptional programs driven by WUSCHEL-CLAVATA feedback for shoot meristem, SHORTROOT-SCARECROW for roo
Ref: Alberts et al., Molecular Biology of the Cell, Chap. Tissue Renewal; NCBI NBK26902 plant development plasticity.
