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High pCO₂ and high H⁺ concentration reduce hemoglobin’s affinity for oxygen, promoting oxygen unloading in tissues.
Ref: NCERT Class 11 Biology Chapter 14: Breathing and Exchange of Gases Respiratory Disorders - Asthma Emphysema Occupational Disorders
Low H⁺ concentration (higher pH) increases hemoglobin's affinity for oxygen, favoring oxygen uptake in the lungs.
Ref: NCERT Class 11 Biology Chapter 14: Breathing and Exchange of Gases Respiratory Disorders - Asthma Emphysema Occupational Disorders
The Bohr effect states that an increase in pCO₂ reduces hemoglobin's affinity for oxygen, promoting oxygen unloading in tissues.
Ref: NCERT Class 11 Biology Chapter 14: Breathing and Exchange of Gases Transport of Carbon Dioxide and Regulation of Respiration
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