The nuclear matrix contains proteins such as:
Nuclear interior contains skeletal framework operationally defined as material insoluble after detergent extraction, DNase digestion and high-salt removal of chromatin. This nuclear matrix comprises lamins A and B at periphery plus internal matrin family proteins Matrin-3, Matrin F, hnRNPs, SAF-A and actin-related proteins that form ten nanometer filaments and fibrogranular networks visible by resinless embedding EM. Matrin-3 is RNA- and DNA-binding protein with zinc-finger domains retaining hyperedited RNAs and anchoring matrix attachment regions to organize loops, mutated in familial amyotro
Ref: Berezney Annu Rev Cell Biol; nuclear matrix lamin matrin-3 scaffold MAR organizes transcription factories.