What is detected using EEG?
Electroencephalography records summed extracellular fields generated by thousands of aligned cortical pyramidal neurons. Action potentials are too brief, approximately one millisecond, and occur asynchronously, so their currents cancel at distant scalp electrodes. Sustained excitatory and inhibitory postsynaptic potentials lasting tens of milliseconds can summate temporally and spatially across cortical columns, creating dipoles detectable noninvasively. Thus raw EEG reflects integrated synaptic drive, not individual spikes, simple ion flux or radioisotope emission. This principle explains sen
Ref: NCERT Biology Class XII Principles on Klenow fill-in labeling, Lehninger Chapter 9 DNA cloning techniques, and Molecular Cloning by Sambrook Chapter 10 documenting end-labeling of cohesive termini.