Which of the following stabilizes the plasma membrane by modulating its fluidity?
Modulation membrane order cholesterol textbook example fluidity homeostasis buffering mechanism dual action concentration dependent. Cholesterol inserts three beta hydroxyl near phospholipid ester carbonyl forming hydrogen bond rigid tetracycle parallel upper ten carbons acyl chains restricting trans gauche isomerization high temperatures decreasing lateral diffusion coefficient from one to zero point five micrometer squared per second and passive permeability small solutes two to three fold measured calcein leakage assays. Low temperatures cholesterol disrupts all trans crystalline lattice in
Ref: Krause & Regen, JACS 2005, Cholesterol regulates fluidity stability buffering phase transition mechanism.
