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#immune defense

9 public questions tagged with this topic.

Which of the following is an antimicrobial peptide?

Antimicrobial peptides such as defensins and cathelicidins are cationic molecules that disrupt microbial membranes by forming pores or micelles. α-Defensins are stored in neutrophil granules and Paneth cells, while β-defensins are produced by epithelial cells. Their broad-spectrum activity constitutes an important chemical barrier of innate immunity at mucosal and epithelial surfaces.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

Which of the following is a physical barrier of innate immunity?

Skin, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

RegIII lectins are resistant against Gram-negative bacteria mainly due to

Presence of LPS shield, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

RegIII lectins preferentially kill

Gram-positive bacteria, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

β-defensins are predominantly active against

Antimicrobial peptides such as defensins and cathelicidins are cationic molecules that disrupt microbial membranes by forming pores or micelles. α-Defensins are stored in neutrophil granules and Paneth cells, while β-defensins are produced by epithelial cells. Their broad-spectrum activity constitutes an important chemical barrier of innate immunity at mucosal and epithelial surfaces.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

Defensins primarily kill microbes by

Antimicrobial peptides such as defensins and cathelicidins are cationic molecules that disrupt microbial membranes by forming pores or micelles. α-Defensins are stored in neutrophil granules and Paneth cells, while β-defensins are produced by epithelial cells. Their broad-spectrum activity constitutes an important chemical barrier of innate immunity at mucosal and epithelial surfaces.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)