Skip to content

#Hepatitis B

6 public questions tagged with this topic.

Which organ is primarily affected by Hepatitis B virus (HBV)?

Hepatitis B virus (HBV) primarily affects the liver, leading to inflammation and potential liver damage. This follows from NCERT principle where the relation explains the outcome clearly for students in simple steps.

Ref: NCERT Biology Textbook for Class XI and XII (Zoology section), Chapter: Biology - Zoology portion covering relevant system and function.

Which plant was engineered to produce edible Hepatitis B vaccine?

Banana was specifically engineered to produce edible Hepatitis B vaccine demonstrating fruit-based oral immunization feasibility. Hepatitis B surface antigen HBsAg 226 amino acid small surface protein self-assembles into 22 nm virus like particles highly immunogenic protective against HBV infection. Early work by Thanavala 1995 expressed HBsAg in transgenic tobacco plants showing assembly. Subsequent collaboration by Arntzen, Mason and colleagues introduced HBsAg gene under fruit specific promoter E8 and constitutive CaMV 35S with endoplasmic reticulum retention signal KDEL into Cavendish bana

Ref: Thanavala et al. PNAS 1995 92:3358 Banana HBsAg; Arntzen 1997 Edible Hepatitis B banana; Lancet.