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#G protein signaling

4 public questions tagged with this topic.

Gαq activates which effector enzyme?

Phospholipase Cβ, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

Inhibition of adenylyl cyclase is mediated by

Adenylyl cyclase catalyzes the conversion of ATP to the second messenger cyclic AMP. The enzyme is stimulated by GTP-bound Gαs and inhibited by GTP-bound Gαi. The resulting changes in cAMP concentration regulate protein kinase A and cyclic-nucleotide-gated channels, linking G-protein-coupled receptors to diverse physiological responses. Careful

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

RGS proteins function to

accelerate GTP hydrolysis, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)