Skip to content
Login Register

#codominant markers

2 public questions tagged with this topic.

Molecular Marker

Which of the following are codominant markers?

Marker inheritance mode determines informativeness. Codominant markers allow differentiation of homozygote and heterozygote, displaying both alleles in heterozygote. Simple Sequence Repeats are multiallelic codominant, with each allele visible as distinct band length. Single Nucleotide Polymorphisms are biallelic codominant, heterozygote shows both nucleotides. RAPD, ISSR and AFLP generate dominant profiles where presence denotes dominant allele, absence recessive, preventing heterozygote distinction. RFLP is also codominant but pairing SSR with SNP represents most widely used codominant combi

Ref: NCERT Biology Class XII Principles on Klenow fill-in labeling, Lehninger Chapter 9 DNA cloning techniques, and Molecular Cloning by Sambrook Chapter 10 documenting end-labeling of cohesive termini.

View Details
Molecular Marker

Which marker type distinguishes homozygotes and heterozygotes?

Simple sequence repeats are codominant markers detecting both alleles at a locus simultaneously as distinct fragment sizes separated by gel or capillary electrophoresis. Homozygous individuals display a single band corresponding to identical repeat length on both homologous chromosomes, while heterozygous individuals show two bands of different lengths, one inherited from each parent. This ability supports accurate allele frequency calculation, heterozygosity estimation and linkage mapping studies. Dominant systems such as RAPD, AFLP and ISSR produce presence-absence profiles that completely m

Ref: NCERT Biology Class XII Principles on Klenow fill-in labeling, Lehninger Chapter 9 DNA cloning techniques, and Molecular Cloning by Sambrook Chapter 10 documenting end-labeling of cohesive termini.

View Details