Bollgard II cotton expresses which genes?
Bollgard II represents stacked trait strategy designed to delay resistance and broaden insecticidal spectrum. First generation Bollgard expressing only Cry1Ac selected resistance alleles in Helicoverpa armigera under continuous exposure. Incorporating second toxin Cry2Ab with different binding site, recognizing distinct aminopeptidase N and ABC transporter, requires insects to carry simultaneous mutations in two receptors to survive, probability drastically lower. Both genes driven by enhanced constitutive promoters provide high dose exceeding LD99 for heterozygous susceptible larvae. Expressi
Ref: ISAAA Brief 43 Bollgard II; Tabashnik Nat Biotechnol 2009 pyramiding; NCBI NBK24601 Cry1Ac Cry2Ab; https://www.isaaa.org/resources/publications/briefs/43/
