bar gene encodes:
Phosphinothricin acetyltransferase belongs to GCN5-related N-acetyltransferase superfamily capable of acetylating amino group of L-phosphinothricin using acetyl-CoA donor. Enzyme encoded by bar gene from Streptomyces hygroscopicus comprises 183 amino acids, small globular protein with conserved motif A for acetyl-CoA binding. Catalytic mechanism involves formation of ternary complex and transfer of acetyl moiety to amino group of PPT, generating herbicidally inactive N-acetyl-PPT that does not interact with glutamine synthetase active site. In transgenic plants, PAT activity rapidly detoxifies
Ref: Thompson EMBO J 1987 PAT acetylates PPT; Wehrmann Nat Biotechnol 1996 bar; NCBI NBK131103 bar encodes PAT; https://www.ncbi.nlm.nih.gov/books/NBK131103/