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#autophosphorylation

3 public questions tagged with this topic.

Cell Signaling Other Signaling Pathways

Sensor kinases in two-component systems autophosphorylate on

Two-component signal-transduction systems consisting of a histidine kinase and a response regulator are widespread in bacteria and plants but essentially absent from animals. The histidine kinase autophosphorylates on a conserved histidine and transfers the phosphoryl group to an aspartate residue on the response regulator, which then executes the cellular response. These systems enable rapid adaptation to environmental changes.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

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Cell Signaling GPCR Pathways - I

Autophosphorylation of CaM-Kinase II leads to

Ca2+-independent activity, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

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Cell Signaling GPCR Pathways - I

CaM-Kinase II remains active after Ca2+ decline due to

autophosphorylation, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

View Details