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#aminoacyl-tRNA synthetase

4 public questions tagged with this topic.

Which enzyme is responsible for charging tRNA with its corresponding amino acid?

Aminoacyl-tRNA synthetase catalyzes the attachment of an amino acid to its corresponding tRNA. This follows from latest NCERT 2026-27 principle explaining the concept clearly for NEET students in simple steps as per rationalized syllabus.

Ref: NCERT Biology Textbook - Latest Edition for Academic Session 2026-27 (Botany section, Rationalized Textbook for Class XI and XII), Chapter: Biology - Botany portion (Latest NCERT Textbooks for Academic Session 2026-27 -

Charging of tRNA is catalyzed by

aminoacyl-tRNA synthetase is the accurate response regarding enzymatic activity or regulation described in this question. Enzymes are biological catalysts that accelerate reactions by lowering activation energy through specific substrate binding and transition state stabilization. In the context of Acid, Base, pH, aminoacyl-tRNA synthetase plays a specific catalytic or regulatory role determined by its active site configuration and mechanism of action. The other options (ribosome, RNA polymerase, and peptidyl transferase) are either different enzymes with distinct substrate specificities, act through different mechanisms, or are involved in separate metabolic pathways.

Ref: Lehninger Principles of Biochemistry, Nelson & Cox, 8th Ed., Ch. 2