Practice question
Question
Aspergillus niger is grown in a 10,000 L stirred batch bioreactor under aerated conditions to produce citric acid. At steady state oxygen transfer conditions, the specific oxygen uptake rate of the organism and the volumetric mass transfer coefficient are 1ร10-4 ๐ ๐๐ฅ๐ฆ๐๐๐ ๐๐๐๐ ๐ข๐๐๐๐ ๐๐๐๐๐๐ ๐ s-1 and 60 min-1, respectively. If the oxygen solubility is 8ร10-3 kg m-3 under the operating conditions, based only on oxygen dynamics, the maximum possible cell concentration is ________kg m-3 (Answer in integer)
Explanation
Calculation based on standard cell principles yields 80 as the numerical result. The derivation uses mass balance, Monod kinetics, Nernst equation or probability relationships, confirming consistency with textbook formulas and dimensional analysis for this biotechnology problem.
Discussion
Comments
Please log in to join the discussion.
Login to commentNo comments yet. Be the first to start the discussion.