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#physiological pH

2 public questions tagged with this topic.

At physiological pH, which amino acid is predominantly in the zwitterionic form?

Glycine is the scientifically accurate answer to this question. Within the study of Amino Acids Basics, this concept is well-established through extensive research and is documented in standard scientific literature. The specific properties, mechanisms, or characteristics of Glycine directly address what is being asked. Among the other options, Lysine, Arginine, and Histidine do not correctly answer this question because they either refer to different concepts, describe properties of other molecules or processes, or represent common misconceptions about this topic.

Ref: Lehninger Principles of Biochemistry, Nelson & Cox, 8th Ed., Ch. 3

Which amino acid has a pKR value that allows it to act as a buffer at physiological pH?

Histidine is obtained by applying the relevant formula or quantitative relationship to the given parameters. In Titration of Amino Acids, numerical problem-solving requires understanding the mathematical relationships between biological variables. The calculation involves substituting the provided values into the appropriate equation and solving systematically. The other options (Glutamate, Arginine, and Lysine) result from common calculation errors such as using incorrect formulas, misidentifying variables, inverting ratios, or making arithmetic mistakes.

Ref: Lehninger Principles of Biochemistry, Nelson & Cox, 8th Ed., Ch. 3