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#HIV

7 public questions tagged with this topic.

ZOOLOGY

Which technique is used for the early detection of HIV in suspected patients?

PCR is used to amplify and detect even small amounts of viral DNA, making it suitable for early HIV detection. This follows from NCERT principle where the relation explains the outcome clearly for students in simple steps.

Ref: NCERT Biology Textbook for Class XI and XII (Zoology section), Chapter: Principles of Inheritance, Molecular Basis of Inheritance and Biotechnology, Topic: Genetics, DNA techniques and applications.

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Gene and Genome

HIV genome is:

Human immunodeficiency virus type 1 possesses lentiviral genome unique among retroviruses for efficient targeting of non-dividing cells. Encapsidated within conical capsid are two identical, non-covalently linked copies of ~9.2 kb positive-sense RNA capped and polyadenylated, bonded at dimer linkage structure near 5' end. Diploidy facilitates recombination and complementation of defects. Each RNA associates with nucleocapsid protein, reverse transcriptase and integrase. After entry, reverse transcriptase copies one RNA into double-stranded proviral DNA integrated into host chromosome by integr

Ref: Freed EO, Virology 2015: HIV Genome is Two Identical RNA Copies, Lentiviral Diploid Genome

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