Late endosomes fuse with:
Endosomal maturation transforms early sorting compartments into degradative organelles preparing cargo for destruction and nutrient recovery. Late endosomes, also termed multivesicular bodies, marked by switch from Rab5 to Rab7 GTPase, more acidic pH near 5.0 to 5.5 due to increased V-ATPase density, and accumulation of intraluminal vesicles formed by ESCRT machinery, move toward microtubule organizing center along microtubules via RILP and dynein. They progressively acquire lysosomal membrane proteins LAMP1, LAMP2 and soluble hydrolases via transport from trans-Golgi network through mannose-6
Ref: Huotari & Helenius, EMBO Journal, 2011: Endosome Maturation and Fusion with Lysosomes.