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#background selection

2 public questions tagged with this topic.

Background selection in MABC helps in:

Background selection accelerates recovery of recurrent parent genome beyond theoretical expectation using genome-wide molecular markers distributed across all chromosomes. While foreground selection tracks donor gene, background selection scans chromosomes unlinked to target using polymorphic SSR or SNP markers distinguishing recurrent and donor alleles by size or sequence. In each backcross generation, individuals carrying target gene are genotyped across background, and those with highest proportion of recurrent parent alleles are chosen as parents for next backcross. Conventional backcrossi

Ref: Frisch M et al. 1999 Crop Sci – background selection for RPG recovery; Ribaut JM MAS strategies

Marker used in mapping QTLs and for background selection:

Molecular markers detect variation at DNA level, offering neutrality, abundance and independence from environmental influence, unlike morphological and cytological markers that are limited and affected by environment. They are ideal for mapping quantitative trait loci controlling complex polygenic traits, tracking introgression of target genes and performing background selection to accelerate recurrent parent genome recovery in breeding programs. Biochemical markers such as isozymes show limited polymorphism. High throughput, codominance and genome coverage make molecular markers indispensable

Ref: NCERT Biology Class XII Principles on Klenow fill-in labeling, Lehninger Chapter 9 DNA cloning techniques, and Molecular Cloning by Sambrook Chapter 10 documenting end-labeling of cohesive termini.