Practice question

Regulative development examples include mammalian identical twins arising after splitting of inner cell mass into two embryonic axes, isolated sea urchin blastomeres forming complete larvae, and amphibian transplantation where presumptive epidermis grafted into neural plate adopts neural fate due to BMP inhibition. In all cases, remaining cells compensate for loss or altered position through inductive reprogramming and community effects. C. elegans development is opposite; lineage is essentially invariant, determinants partitioned rigidly, ablation permanently removes tissue. Such mosaic behavior lacks compensation and potency equals fate, illustrating autonomous rather than conditional regulation and not regulative development.