Practice question
Question
When the 4 blastomere pairs of an 8-cell stage tunicate embryo are dissociated, each forms most of the
structures it would have formed in the embryo. However, the notochord and nervous system require
interactions between different blastomeres. Which concl
Explanation
Tunicate embryos at the eight-cell stage exhibit predominantly autonomous development, as dissociated blastomere pairs still differentiate into most tissues normally derived from them, reflecting segregation of determinants like macho-1 for muscle. However, notochord and nervous system lineages deviate from this rule, failing to form in isolation and requiring cell-cell interaction between animal and vegetal partners. Inductive signals involving FGF and BMP antagonism from presumptive notochord precursors influence neighboring ectoderm. Therefore most lineages demonstrate autonomous specification, while notochord and neural fate exemplifies conditional specification dependent on extrinsic instructive communication for proper induction.
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