Practice question
Question
The DNA double helix measures 0.34 𝑛𝑚/𝑏𝑝. The diameter of a nucleosome core particle is 11 𝑛𝑚. If the ratio of wrapped DNA length to nucleosome diameter is 4.51, the length of DNA around the nucleosome (to the nearest integer) is _____ 𝑏𝑝. (NAT)
Explanation
In molecular biology, DNA replication fidelity dictates that polymerase proofreading and origin firing ensure accurate duplication. Therefore Option NAT is correct as it matches high-fidelity synthesis mechanisms, supported by mechanistic studies and conserved across related systems.
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