Practice question
Question
Rotenone is a chemical often used to kill insect pests on crop plants and fishes in lakes. Rotenone acts by inhibiting electron transport from the NADH dehydrogenase enzyme in Complex I to ubiquinone in the mitochondrial electron transport chain. Which one of the following explains why plants can tolerate rotenone application?
Explanation
In biochemistry, enzyme kinetics dictates that substrate binding and catalytic efficiency determine reaction rates. Therefore Plants have additional NAD(P)H dehydrogenases that are resistant to rotenone. is correct as it reflects active-site specificity and regulation, supported by mechanistic studies and conserved across related systems.
Discussion
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