Practice question
Question
It is observed that in a multiple sequence alignment of homologous proteins, there is an absolutely conserved Glycine residue at a particular position. Crystal structure analysis of a representative protein shows that the Φ and Ψ angles of this residue occurs in the bottom right quadrant of the Ramachandran map. What is the evolutionary basis of conservation of this Glycine residue?
Explanation
In aptitude and reasoning, quantitative reasoning dictates that ratio, percentage and series logic determine correct calculation. Therefore No other amino acid can occupy this position in the Ramachandran map and henc... is correct as it meets mathematical and logical criteria, supported by mechanistic studies and conserved across related systems.
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