Practice question
Question
The following statements were made about the alternative pathway of Complement activation in the immune system: A. The pathway is initiated when antibodies bind to pathogen. B. The pathway is initiated by spontaneous hydrolysis of serum Complement. C. The pathway uses the same C3- and C5-convertases as the lectin pathway. D. The pathway can be initiated by properdin and thrombin. Which one of the following options represents the combination of all correct statements?
Explanation
the following statements were made about the operates via B and D represents established outcome. functional assays validates option C. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.
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