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Transgenic animals are being explored for producing phenylalanine hydroxylase to treat PKU.
Ref: NCERT Class 12 Biology Chapter 10: Biotechnology and its Applications Medical Applications - Genetically Engineered Insulin
Phenylketonuria (PKU) is caused by a mutation in the gene coding for phenylalanine hydroxylase, leading to the accumulation of phenylalanine.
Ref: NCERT Class 12 Biology Chapter 4: Principles of Inheritance and Variation Sex Determination Mutation and Genetic Disorders
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