5 public questions tagged with this topic.
Natural killer (NK) cells are a part of the innate immune system and destroy virus-infected and cancerous cells.
Ref: NCERT Class 12 Biology Chapter 7: Human Health and Disease Cancer - Causes Types Treatment Metastasis
Natural killer (NK) cells are part of the innate immune system and help eliminate virus-infected and cancerous cells.
Ref: NCERT Class 12 Biology Chapter 7: Human Health and Disease Immunity - Innate Immunity - Barriers and Interferons
Natural killer cells survey the surface of potential target cells for the presence of MHC class I molecules. Cells that lack or down-regulate MHC I, a common strategy of viruses and tumors, are recognized as missing-self and are killed by release of perforin and granzymes. NK cells therefore provide an important innate barrier against transformed and virally infected cells.
Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)
Natural killer cells survey the surface of potential target cells for the presence of MHC class I molecules. Cells that lack or down-regulate MHC I, a common strategy of viruses and tumors, are recognized as missing-self and are killed by release of perforin and granzymes. NK cells therefore provide an important innate barrier against transformed and virally infected cells.
Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)
Macrophages and neutrophils, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.
Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)
