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Practice question

Question

Opsonization enhances phagocytosis by

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Explanation

Opsonization is the coating of a particle with host proteins that facilitate its recognition and uptake by phagocytes. Complement fragments such as C3b and acute-phase proteins such as C-reactive protein function as opsonins. Binding of these molecules to microbial surfaces engages complement receptors or Fc receptors on macrophages and neutrophils, dramatically enhancing phagocytosis.