Practice question
Question
GURKE (GK) gene encodes:
Explanation
GURKE, synonymous with PASTICCINO3 and EMB22, encodes ACC1 cytosolic homomeric acetyl-CoA carboxylase catalyzing ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA precursor for very-long-chain fatty acids, sphingolipids, cuticular waxes, and seed triacylglycerols. VLCFA-derived lipid signals modulate cytokinin and auxin homeostasis in globular embryo apex. gurke mutants fail to partition apical dome into three subdomains: two cotyledon anlagen, central WUS-expressing shoot organizing center, and CUC-expressing boundary regions. Seedlings display fused cotyledons and disrupted meristems, directly linking lipid metabolism to developmental fate patterning and meristem organization.
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