The main function of Teichoic acids in Gram-positive bacteria is:
Gram positive wall comprises thick peptidoglycan crosslinked peptides providing rigidity against internal turgor up to 20 atmospheres. Embedded anionic polymers wall teichoic acids covalently linked phosphodiester to C6 hydroxyl N acetylmuramic acid and lipoteichoic acids anchored diacylglycerol into membrane extending outward. Structure polyglycerol phosphate or polyribitol phosphate modified D alanylation introducing positive charge modulating autolytic enzymes. Physiological roles encompass providing cell wall integrity by controlling autolysin Atl Atl mediated remodeling preventing prematu
Ref: Brown et al., Nat Rev Microbiol 2013, Teichoic acids provide cell wall integrity in Gram-positive.
