Practice question
Question
In hybridoma technology, B cells are fused with:
Explanation
Hybridoma technology fuses antibody-producing B lymphocytes with immortal myeloma cells to generate continuous hybrid lines secreting monoclonal antibody. Polyethylene glycol mediated fusion, followed by HAT medium selection, eliminates unfused parents. Resultant hybridomas combine specific antibody specificity with perpetual growth, revolutionizing therapeutic and diagnostic antibody production.
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