Practice question
Question
Phagocytosis enhanced by coating the surface of antigen is called:
Explanation
Opsonization coats microbial surfaces with opsonins such as IgG and complement fragment C3b, enhancing recognition by phagocyte Fc and complement receptors. This coating bridges pathogen to phagocyte, promoting adhesion, ingestion and respiratory burst killing. Deficiency in opsonization explains recurrent infections with encapsulated bacteria lacking effective phagocytic clearance.
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