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Question

Which of the following statement is correct for Heterozygote advantage?

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Choose one · Correct answer highlighted

Explanation

Balancing selection maintains HbS allele because heterozygotes resist Plasmodium falciparum malaria while homozygotes suffer sickle disease. This heterozygote advantage explains high allele frequency in malaria-endemic regions, distorting Hardy-Weinberg equilibrium, unrelated to founder effect.

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