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Question

Which of the following is the major immunoglobulin in human serum, accounting for 80% of the immunoglobulin pool?

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Choose one · Correct answer highlighted

Explanation

IgG dominates human serum, constituting roughly 75-80% of total immunoglobulins. It is monomeric, longest half-life (~21 days), crosses placenta, opsonizes pathogens and activates complement via classical pathway. Its abundance reflects secondary immune responses and memory establishment.

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