Practice question
Question
Loss of which of the following classes of molecules on the surface of a tumor cell target would result in reduced susceptibility to killing by host immune cells?
Explanation
The principle of cellular compartmentalization and cell cycle explains that SNARE-mediated trafficking, Hayflick limit, P53 and cyclin regulation control proliferation. Hence MHC class I fits best because it aligns with membrane trafficking and cell cycle control, as documented in authoritative sources on cell biology.
Discussion
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