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Question

Ligand for TLR3 receptor is:

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Choose one · Correct answer highlighted

Explanation

TLR3 is endosomal pattern recognition receptor recognizing double-stranded RNA produced during viral replication. Binding dsRNA recruits TRIF adaptor, activating IRF3 and NF-kB pathways leading to type I interferon production. LPS binds TLR4, lipopeptides TLR2, flagellin TLR5, not TLR3.

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